Etika Pemilihan Ciri Non-Medis Embrio: Analisis Bioetika atas Praktik ‘Designer Baby’ dalam IVF Modern

Authors

  • Anggi Agustin Universitas Islam Negeri Sunan Gunung Djati
  • Anita Fitriani Universitas Islam Negeri Sunan Gunung Djati
  • Clarissa Syahnaz Aulia Universitas Islam Negeri Sunan Gunung Djati
  • Tri Cahyanto Universitas Islam Negeri Sunan Gunung Djati

DOI:

https://doi.org/10.61132/jupenkifb.v2i1.890

Keywords:

Beneficence, Designer Baby, Modern IVF, Non-Medical Embryo Selection, Reproductive Bioethics

Abstract

Advances in in vitro fertilization (IVF) technology have expanded the scope of reproductive interventions, from simply addressing infertility to enabling genetic selection of embryos through preimplantation genetic testing (PGT). This advancement not only enables the detection and prevention of severe genetic diseases, but also opens up opportunities for the selection of non-medical traits such as intelligence potential, physical characteristics, or specific polygenic scores, giving rise to the phenomenon of “designer babies.” This development presents complex bioethical issues related to human dignity, social justice, biological safety, and the right of children to have an open future. This paper aims to analyze the ethical issues of selecting non-medical characteristics of embryos in modern IVF through a literature review using a biomedical ethics framework, including the principles of autonomy, beneficence, non-maleficence, and justice. The findings show that the application of technology for non-medical purposes is still fraught with scientific risks, biological uncertainties, the potential for commercialization of humans, and the threat of socio-biological inequality. This analysis emphasizes the need to restrict the use of technology to clear medical indications, increase regulation and governance, and involve the public in policy formulation. Thus, advances in reproductive technology must be accompanied by strict ethical considerations so as not to sacrifice individual dignity and the value of justice in society.

References

Afshari, M., Shahini, Z., & Kordkatouli, M. (2025). Human Embryo Genetic Manipulation from the Point of View of Bioethics and Human Rights. Gene, Cell and Tissue, 12(12), e166959. https://doi.org/10.5812/gct-166959.

https://doi.org/10.5812/gct-166959

Al Shakaki, A. (2019). Bioethical deliberation on genomic testing: Islamic perspectives (Master's thesis, Hamad Bin Khalifa University (Qatar)).

Ayanoğlu, F. B., Elçin, A. E., & Elçin, Y. M. (2020). Bioethical issues in genome editing by CRISPR-Cas9 technology. Turkish Journal of Biology, 44(2), 110-120. https://doi.org/10.3906/biy-1912-52.

https://doi.org/10.3906/biy-1912-52

Bioethics, N. (2018). Genome editing and human reproduction: social and ethical issues. London: Nuffield Council on Bioethics.

Budiyanti, R. T. (2015). Aspek Etika Pre-implantation Genetic Diagnosis (PGD) pada Teknologi Bayi Tabung. Cermin Dunia Kedokteran, 42(7), 542-544.

Cohen, I. G., & Adashi, E. Y. (2020). Heritable Human Genome Editing: The International Commission Report. JAMA, 324(19), 1941-1942.

https://doi.org/10.1001/jama.2020.19059

Foulon, L., Neuhaus, C., Grunschlag, M., Eilmus, A., & Kearns, L. (2024). Sex selection, genetic analysis, and designer babies [Teaching module].

Furrer, R. A., Barlevy, D., Pereira, S., dkk. (2024). Public Attitudes, Interests, and Concerns Regarding Polygenic Embryo Screening. JAMA Network Open, 7(5): e2410832.

https://doi.org/10.1001/jamanetworkopen.2024.10832

Greely, H. T. (2019). CRISPR'd babies: human germline genome editing in the 'He Jiankui affair'. Journal of Law and the Biosciences, 6(1), 111-183.

https://doi.org/10.1093/jlb/lsz010

Guo, C., Ma, X., Gao, F., & Guo, Y. (2023). Off-target effects in CRISPR/Cas9 gene editing. Frontiers in bioengineering and biotechnology, 11, 1143157.

https://doi.org/10.3389/fbioe.2023.1143157

Halpern, J., O'Hara, S. E., Doxzen, K. W., Witkowsky, L. B., & Owen, A. L. (2019). Societal and ethical impacts of germline genome editing: How can we secure human rights?. The CRISPR Journal, 2(5), 293-298.

https://doi.org/10.1089/crispr.2019.0042

Janssens, A. C. J. W. (2016). Designing babies through gene editing: science or science fiction?. Genetics in Medicine, 18(12), 1186-1187.

https://doi.org/10.1038/gim.2016.28

Kamenova, K., & Haidar, H. (2022). The First Baby Born After Polygenic Embryo Screening: Key Issues Through the Lens of Experts and Science Reporters. Voices in Bioethics, 8.

https://doi.org/10.52214/vib.v8i.9467

Prasath, S. S. (2023). Designer Babies: Revealing the Ethical and Social Implications of Genetic Engineering in Human Embryos. International Journal of Science and Research (IJSR), 12 (7), 692.

https://doi.org/10.21275/SR23710130528

Romero, U. K. (2023). Designer Babies are No Longer Science Fiction: What are The Ethical Considerations? Bincang Sains dan Teknologi (BST), 2(3), 124-132.

https://doi.org/10.56741/bst.v2i03.437

Savulescu, J. (2012). Procreative Beneficence: Why We Should Select the Best Children. Arguing About Bioethics, London, Routledge, 74-82.

Shabana, A. (2022). Between treatment and enhancement: Islamic discourses on the boundaries of human genetic modification. Journal of Religious Ethics, 50(3), 386-411.

https://doi.org/10.1111/jore.12404

Siermann, M., Valcke, O., Vermeesch, J. R., Raivio, T., Tšuiko, O., & Borry, P. (2024). "Are we not going too far?": Socio-ethical considerations of preimplantation genetic testing using polygenic risk scores according to healthcare professionals. Social Science & Medicine, 343, 116599.

https://doi.org/10.1016/j.socscimed.2024.116599

Soni, S., & Savulescu, J. (2021, October 20). Polygenic Embryo Screening: Ethical and Legal Considerations. Hastings Center Bioethics Forum.

Wiley, L., Cheek, M., LaFar, E., Ma, X., Sekowski, J., Tanguturi, N., & Iltis, A. (2025, June). The ethics of human embryo editing via CRISPR-Cas9 technology: A systematic review of ethical arguments, reasons, and concerns. In Hec Forum (Vol. 37, No. 2, pp. 267-303). Dordrecht: Springer Netherlands.

https://doi.org/10.1007/s10730-024-09538-1

Downloads

Published

2026-01-07

How to Cite

Anggi Agustin, Anita Fitriani, Clarissa Syahnaz Aulia, & Tri Cahyanto. (2026). Etika Pemilihan Ciri Non-Medis Embrio: Analisis Bioetika atas Praktik ‘Designer Baby’ dalam IVF Modern. Jurnal Pendidikan Kimia, Fisika Dan Biologi, 2(1), 20–36. https://doi.org/10.61132/jupenkifb.v2i1.890

Similar Articles

You may also start an advanced similarity search for this article.