Inovasi Terbaru dalam Terapi Gen, Terapi Berbasis Sel, dan Pengembangan Obat Anti Kanker dari Bahan Alam
DOI:
https://doi.org/10.61132/jucapenbi.v2i1.150Keywords:
anti-cancer drugs, cancer treatment innovations, CAR-T, cell-based therapy, Gene therapy, natural productsAbstract
Cancer therapy has undergone remarkable advancements in recent decades, driven by innovations in gene therapy, cell-based therapy, and the development of anti-cancer drugs from natural products. Gene therapy offers the possibility of correcting genetic mutations that cause cancer, while cell-based therapies, such as CAR-T cell therapy, provide personalized and effective solutions. Additionally, the exploration of natural compounds continues to be a promising approach in anti-cancer drug development. This paper discusses recent progress in these three fields, highlighting their potential, challenges, and implications for future clinical applications.
References
Chen, L., et al. (2019). Analisis ekspresi gen pada sel kanker. Journal of Cancer Research, 75(10), 2011–2018.
Huang, Y., et al. (2019). Genome editing dengan CRISPR-Cas9. Journal of Genetics and Genomics, 46(3), 123–130.
Kim, J., et al. (2019). Genome editing with CRISPR-Cas9 in human cells. Journal of Genetics and Genomics, 46(5), 247–254.
Lander, E. S. (2016). The heroes of CRISPR. Cell, 164(1–2), 18–28.
Li, D., et al. (2019). Genome editing with CRISPR-Cas9 in human stem cells. Nature Communications, 10(1), 1–9.
Liang, Y., et al. (2020). Pengembangan terapi sel induk untuk pengobatan penyakit degeneratif. Journal of Stem Cell Research, 15(1), 1–8.
Liu, X., et al. (2020). Pengembangan terapi gen dengan CRISPR-Cas9. Journal of Biotechnology, 30(2), 100–108.
Nugroho, A. E., et al. (2020). Analisis ekspresi gen pada sel kanker. Jurnal Biologi dan Kedokteran, 10(1), 1–8.
Smith, S. E., et al. (2017). Mycorrhizal fungi in soil ecology. Soil Biology and Biochemistry, 116, 53–61.
Sutanto, H., et al. (2020). Pengembangan terapi gen dengan CRISPR-Cas9. Jurnal Ilmu Kedokteran Indonesia, 11(2), 123–132.
Tang, Y., et al. (2018). Gene therapy for genetic diseases. Journal of Genetics and Genomics, 45(9), 453–464.
Wahyuni, S., et al. (2019). Potensi tanaman obat sebagai anti-kanker. Jurnal Farmasi Indonesia, 13(1), 45–54.
Wang, Y., et al. (2020). CRISPR-Cas9-mediated gene editing in human cells. Proceedings of the National Academy of Sciences, 117(15), 8312–8317.
Widyastuti, A., et al. (2019). Pengembangan terapi sel induk untuk pengobatan penyakit degeneratif. Jurnal Kedokteran dan Kesehatan, 12(2), 100–108.
Zhang, J., et al. (2020). CRISPR-Cas9-mediated gene editing in cancer therapy. Journal of Cancer Research, 76(12), 2512–2519.
